Select a class of APIs and select a formulation strategy to enable these APIs to be developed into medicines: Phase Appropriateness Essay, UCD, Ireland

Select a class of APIs and select a formulation strategy to enable these APIs to be developed into medicines. Pretend you are the first one to come up with this idea. You can pick anything – e.g. long-acting injectable suspensions or cocrystallization for poorly water-soluble APIs, a metal-organic framework for controlled release of APIs, pegylation for therapeutic proteins, etc. If based on an existing idea/core paper, please cite the paper at the very start of the assignment.

Outline the issue/problem that your new formulation idea will resolve. Explain what your idea is and how it will work. Indicate what type of API and/or routes of administration it will be useful for.
Describe how your idea is better than other formulation strategies that exist and the impact it could have in the world.
Outline the experiments that you would do to prove your idea would work over a period of 4 years.
Select examples of APIs you would test and excipients you would use and give a rationale for your selection.
Describe the actual experiments and methods you would do.
Describe the analysis you would do to determine if your formulation had worked – include the analytical equipment you would use for the characterization of your formulation.
Estimate the budget you would need to work on this idea for 4 years.
Describe the outputs you would generate at the end of the 4 years.

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